Protons block the dark current of isolated retinal rods.
نویسندگان
چکیده
منابع مشابه
Morphogenesis of the Retinal Rods
The morphogenesis of the retinal rods has been studied with the electron microscope in white mice from birth up to the 16th day of age. Observations have been mainly concentrated on specimens of the 8th and 12th days and on the differentiation of the inner and outer segments of the retinal rods. In the morphogenesis of the outer segment three main stages have been considered. The first stage co...
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Ion channels directly activated by cyclic nucleotides are present in the plasma membrane of retinal rod outer segments. These channels can be modulated by several factors including internal pH (pH(i)). Native cyclic nucleotide-gated channels were studied in excised membrane patches from the outer segment of retinal rods of the salamander. Channels were activated by cGMP or cAMP and currents as ...
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The visual pigment complex within a single retinal rod and, cone can be studied by microspectrophotometry in order to identify the pigments during the light < > dark reactions. Specimen areas in the rods and cones of the order 2 M were scanned at relatively low magnifications from 340 to 900 mn. Freshly isolated frog (Rana pipiens) retinal rods and cones were rapidly scanned ivith the microspec...
متن کاملEpigenomic landscapes of retinal rods and cones
Rod and cone photoreceptors are highly similar in many respects but they have important functional and molecular differences. Here, we investigate genome-wide patterns of DNA methylation and chromatin accessibility in mouse rods and cones and correlate differences in these features with gene expression, histone marks, transcription factor binding, and DNA sequence motifs. Loss of NR2E3 in rods ...
متن کاملMethod of targeted delivery of laser beam to isolated retinal rods by fiber optics
A method of controllable light delivery to retinal rod cells using an optical fiber is described. Photo-induced current of the living rod cells was measured with the suction electrode technique. The approach was tested with measurements relating the spatial distribution of the light intensity to photo-induced current. In addition, the ion current responses of rod cells to polarized light at two...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1983
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.80.7.1892